From The Guardian: Mass Extinction is possible with large amounts of carbon dioxide
Put enough CO2 into the system all at once, and push the life-sustaining carbon cycle far enough out of equilibrium, and it might escape into a sort of planetary failure mode, where processes intrinsic to the Earth itself take over, acting as positive feedback to release dramatically more carbon into the system. This subsequent release of carbon would send the planet off on a devastating 100-millennia excursion before regaining its composure. And it wouldn’t matter if CO2 were higher or lower than it is today, or whether the Earth was warmer or cooler as a result. It’s the rate of change in CO2 that gets you to Armageddon.